Why does pradaxa cause heartburn

But another way pills can irritate the esophagus is by local irritation. If the pill gets stuck or simply does not move through down the esophagus, it can cause severe local inflammation. This intense and focused inflammation can cause severe symptoms, chest pain, swallowing pain and even perforation requiring surgery.

Pill esophagitis is not Mickey Mouse. Historically, tetracycline antibiotics, NSAIDs and the biphosphanates have been the most frequent offenders. Three clusters of case reports of oesophageal ulcer have been reported to Boehringer Ingelheim from around the world.

In addition, cases of positive re-challenge have been reported. Boehringer Ingelheim has updated the data sheet for Pradaxa. Medsafe continues to monitor the safety of Pradaxa, as for all medicines. Information for consumers and caregivers Always take Pradaxa with food and a full glass of water to help the capsule get to your stomach. Tell your doctor right away if you have back pain, tingling, numbness, muscle weakness especially in your legs and feet , loss of control of the bowels or bladder incontinence.

Tell your healthcare provider or get medical help right away if you get any of the following symptoms of a serious allergic reaction to PRADAXA Capsules:.

Tell your healthcare provider if you have any side effect that bothers you or does not go away. For more information, ask your doctor or pharmacist and be sure to also access the Medication Guide. Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www. Then use the Doctor Discussion Guide for an easy way to get the conversation started during your next office visit. If you take PRADAXA and receive spinal anesthesia or have a spinal puncture, your healthcare provider should watch you closely for symptoms of spinal or epidural blood clots.

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