How do prednisone work




















These conditions can lead to nephrotic syndrome. As a result, large amounts of protein leaks into the urine. This in turn reduces the amount of protein in your blood, known as proteinuria. Prednisone is used to help lower proteinuria in these disorders.

People taking prednisone can also experience higher blood sugar, which is a special concern for those with diabetes. Therefore, some precautions need to be taken. Your healthcare provider will weigh the possible benefits and side effects when giving this and other medications. Many people have benefitted from prednisone without serious side effects. Talking to your healthcare provider, using your medication as instructed, and taking the necessary precautions, can help you benefit from prednisone while managing side effects.

Here are some things you can do to keep yourself healthy:. Skip to main content. September 23, , pm EDT. Side effects depend on the dose of medication you receive and may include:. When using an inhaled corticosteroid, some of the drug may deposit in your mouth and throat instead of making it to your lungs. This can cause:. If you gargle and rinse your mouth with water — don't swallow — after each puff on your corticosteroid inhaler, you may be able to avoid mouth and throat irritation.

Some researchers have speculated that inhaled corticosteroid drugs may slow growth rates in children who use them for asthma. Injected corticosteroids can cause temporary side effects near the site of the injection, including skin thinning, loss of color in the skin, and intense pain — also known as post-injection flare.

Other signs and symptoms may include facial flushing, insomnia and high blood sugar. Doctors usually limit corticosteroid injections to three or four a year, depending on each patient's situation.

Corticosteroids may cause a range of side effects. But they may also relieve the inflammation, pain and discomfort of many different diseases and conditions. Talk with your doctor to help you better understand the risks and benefits of corticosteroids and make informed choices about your health. There is a problem with information submitted for this request.

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A single copy of these materials may be reprinted for noncommercial personal use only. This content does not have an English version. This content does not have an Arabic version. See more conditions. Prednisone and other corticosteroids. Products and services. Prednisone and other corticosteroids Weigh the benefits and risks of corticosteroids, such as prednisone, when choosing a medication. By Mayo Clinic Staff. Thank you for Subscribing Our Housecall e-newsletter will keep you up-to-date on the latest health information.

Please try again. Something went wrong on our side, please try again. Show references Ritter JM, et al. The pituitary and the adrenal cortex. Elsevier; Accessed Oct. Your doctor will probably reduce your dose before you stop treatment completely. This is to reduce the risk of withdrawal symptoms. If you miss a dose of prednisolone, take it as soon as you remember.

If you don't remember until the following day, skip the missed dose. If you forget doses often, it may help to set an alarm to remind you. You could also ask your pharmacist for advice on other ways to help you remember to take your medicine. The higher the dose of prednisolone that you take, the greater the chance of side effects. You are less likely to get side effects if you take a relatively low dose of less than 20mg prednisolone daily.

Some side effects, such as stomach upset or mood changes, can happen straight away. Others, such as getting a rounder face, happen after weeks or months. Common side effects happen in more than 1 in people. Keep taking the medicine, but tell your doctor if they bother you or don't go away:. You are more likely to have a serious side effect if you take a higher dose more than 20mg daily of prednisolone or if you have been taking it for more than a few weeks. In rare cases, it's possible to have a serious allergic reaction anaphylaxis to prednisolone.

You could be having a serious allergic reaction and may need immediate treatment in hospital. These are not all the side effects of prednisolone. For a full list see the leaflet inside your medicines packet. You can report any suspected side effect to the UK safety scheme. Long periods of prednisolone treatment can slow down the normal growth of children and teenagers. Your child's doctor will watch their growth carefully while they are taking steroids.

That way any slowing of growth can be picked up promptly and treatment changed if necessary. Talk to your doctor about the risks of giving prednisolone to your child if you are concerned. Prednisolone isn't usually recommended in pregnancy unless the potential benefits outweigh the risks. Prednisolone has occasionally been linked to problems in the first 12 weeks of pregnancy.

High doses or long-term use can also affect the unborn baby's growth. If you take prednisolone in pregnancy, the baby's growth will be checked often. You can usually take prednisolone while you're breastfeeding. However, prednisolone can get into breast milk. If you're taking a high dose of prednisolone the baby may need to be monitored for side effects. For safety, it's usually recommended that you wait 3 to 4 hours after taking your dose of prednisolone before feeding your baby or expressing milk.

There are many medicines that interfere with the way prednisolone works, or that increase the risk of side effects. It's very important you check a medicine is safe to take with prednisolone before you start taking it.

This includes some medicines that you buy over the counter like aspirin and anti-inflammatory painkillers such as ibuprofen. There's very little information about taking herbal remedies and supplements with prednisolone. For safety, tell your doctor or pharmacist if you take any other medicines, including herbal remedies, vitamins or supplements. Steroids mimic the effects of hormones your body naturally produces in your adrenal glands. The adrenal glands sit on top of your kidneys.

When prescribed in doses higher than your body's usual levels, steroids like prednisolone dampen inflammation. This can reduce the symptoms of inflammatory conditions, such as arthritis and asthma. Steroids also damp down your immune system, which can help in autoimmune illnesses like rheumatoid arthritis , where your immune system mistakenly attacks its own tissues. For other illnesses, you may not feel any better even though the medicine is helping you.

This may be the case if you're taking prednisolone to stop your symptoms getting worse or to prevent a problem happening for example after an organ transplant. You may need to take it for longer - even for many years or the rest of your life. If you have to take prednisolone for more than a few weeks, the chances are that you will put on weight. Prednisolone can make you hungrier and retain water, so it can be quite challenging to avoid weight gain.

Try to eat well without increasing your portion sizes. Regular exercise will also help to keep your weight stable. Once you stop taking prednisolone, any issues around increased appetite or water retention should return to normal. It can be dangerous to stop taking prednisolone suddenly, especially if you have been on a high dose for a long time.

Your health condition may flare up again. You may also get extra side effects including:. These side effects are most likely to happen if you have taken prednisolone for more than a few weeks or you take more than 40mg daily. Your doctor will probably want to reduce your dose gradually over several weeks to prevent these side effects. Do not stop taking prednisolone without talking to your doctor - you will need to reduce the dose gradually. Taking prednisolone for many months or years can have several harmful effects on your body.

It can lead to:. If you have to take prednisolone for a long time, there are steps you can take to stay as healthy as possible:. Taking prednisolone makes you more likely to catch infections such as flu , the common cold and chest infections. Keep away from people with an infectious disease, especially chickenpox or shingles.



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